Which of the following describe roles played by HCO3-? 1. HCO3– levels vary directly with Cl- levels. 2. It is the primary vehicle for blood carbon dioxide transport. 3. It plays a key role in acid-base homeostasis
a. 1, 2, and 3
b. 1 and 3 only
c. 2 only
d. 2 and 3 only
ANS: D
HCO3– plays an important role in acid-base homeostasis and is the strong base in the bicar-bonate-carbonic acid buffer pair. HCO3– is the primary means for transporting carbon dioxide from the tissues to the lungs. The ratio of HCO3– to carbonic acid in healthy individuals is main-tained near 20:1.
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