A client who has gastroesophageal reflux disease (GERD) has been taking proton pump inhibitors (PPIs) for many years. The nurse discusses which potential complication of this long-term therapy?
1. Increased risk of anemia
2. Increased risk of osteopenia
3. Increased risk of hypertension
4. Increased risk of intestinal irritation
2
Rationale 1: Anemia is not a consequence of long-term use of PPIs.
Rationale 2: Long-term use of PPIs increases risk of osteopenia and osteoporosis.
Rationale 3: Hypertension is not a consequence of long-term use of PPIs.
Rationale 4: Intestinal irritation is not a consequence of long-term use of PPIs.
Global Rationale: Long-term use of PPIs increases risk of osteopenia and osteoporosis. It does not increase risk of anemia, hypertension, or intestinal irritation.
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