The nurse is caring for a patient with atropine poisoning. What drug will the nurse administer to reverse these effects?
A) Bethanechol
B) Neostigmine
C) Edrophonium
D) Physostigmine
D
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Physostigmine can be used as an antidote for atropine poisoning. A slow intravenous injection of 0.5 to 4 mg (depending on the weight of the patient and the severity of the symptoms) usually reverses the delirium and coma of atropine toxicity. Physostigmine is metabolized rapidly, so the injection may need to be repeated every 1 to 2 hours until the atropine has been cleared from the system.
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