An obese patient has asked her nurse practitioner to prescribe sibutramine. What variable will most affect the nurse's decision?
A) Sibutramine has been taken off the market due to adverse cardiovascular effects.
B) Sibutramine is prohibitively expensive and is not covered by most insurers.
C) The use of sibutramine requires weekly blood work.
D) Sibutramine must be combined with an anticholinergic drug in order to potentiate its effects.
A
Feedback:
Until recently, health care providers used sibutramine, a drug that suppresses appetite by inhibiting the reuptake of the neurotransmitters norepinephrine and serotonin, in the management of obesity. The drug is no longer available in the United States because a clinical study demonstrated an increased risk of cardiovascular events such as heart attack and stroke with its use.
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