The most common form of hemophilia is a defect in blood clotting factor VIII, which is caused by a recessive form of a gene carried on the X chromosome. A girl is born with hemophilia. Both parents have normal phenotype
Which of the following might explain this girl's
hemophilia?
A. A nondisjunction event in sperm
production resulted in her receiving X and Y
chromosomes from her father, and an X from
her mother; she is XXY.
B. Nondisjunction during egg formation
resulted in her receiving no X chromosome
from her mother, but an X from her father;
she is XO.
C. Nondisjunction during sperm formation
resulted in her receiving no sex chromosome
from her father and an X chromosome from
her mother; she is XO.
D. Nondisjunction during egg formation
resulted in her receiving two X chromosomes
from her mother and an X chromosome from
her father; she is XXX.
E. She inherited an X chromosome from her
father and the X carrying the defective allele
from her mother.
C
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a. True b. False
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