A nurse transcribes a new prescription for potassium penicillin G given intravenously (IV) every 8 hours and gentamicin given IV every 12 hours. Which is the best schedule for administering these drugs?
a. Give the penicillin at 0800, 1600, and 2400; give the gentamicin (Garamycin) at 1800 and 0600.
b. Give the penicillin at 0800, 1600, and 2400; give the gentamicin (Garamycin) at 1200 and 2400.
c. Give the penicillin at 0600, 1400, and 2200; give the gentamicin (Garamycin) at 0600 and 1800.
d. Give the penicillin every 8 hours; give the gentamicin (Garamycin) simultaneously with two of the penicillin doses.
ANS: A
Gentamicin should never be administered concurrently with penicillin, because they will interact, and the penicillin may inactivate the aminoglycoside. All the other options show concurrent administration.
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