Discuss the current literature recommendations for supplementation of omega-3-fatty acids, glutamine, arginine and antioxidants in nutrition support during sepsis

Question

What will be an ideal response?

Answer 1

Currently, arginine supplementation is not suggested in sepsis and negative outcomes have been documented with its use. There is some controversy in the literature regarding the use of glutamine for critically ill patients as the studies have studied glutamine both enterally and parenterally – in a variety of critically ill populations and in a combination with other nutrients. It is likely that the controversy lies with these differences in research design and in the populations that were studied. Previous trials noted benefit of glutamine supplementation. Omega-3- fatty acids and antioxidants should be considered in patients with acute lung injuries or adult respiratory distress syndrome. Otherwise, more research is needed in regards to other critical illnesses, such as sepsis, since negative and potentially harmful outcomes may occur – the literature needs to continue to clarify its use.