When platelets are activated, all of the following occur except:
a. a-Granule contents are released.
b. Smooth cytoplasmic membrane margins change to spiny projections.
c. The prostaglandin (eicosanoid synthesis) pathway is activated.
d. Adenosine diphosphate (ADP) release is inhibited.
ANS: D
When the platelet is activated, storage ADP is released from the platelet and then binds to its ligand on the platelet membrane, acting as an agonist. All the other changes listed do occur when the platelet is activated.
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