How does a Philadelphia chromosome occur, and what condition does it cause?

What will be an ideal response?


Ninety percent of patients with the fatal cancer chronic myelogenous leukemia (CML cancer) have a chromosomal mutation in their myeloblasts caused by a reciprocal translocation event between chromosome 22 and chromosome 9. The defective chromosome 22 is called the Philadelphia chromosome.

Biology & Microbiology

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Scientists have been able to clone

a. sheep. b. cats. c. rabbits. d. pigs. e. all of these.

Biology & Microbiology

Microbes are considered an abiotic factor within an ecosystem

Indicate whether the statement is true or false

Biology & Microbiology

A scientist is working in a lab sequencing DNA. After reading the results from a column of gel scanned in a fluoroscope, she determines that the sequence of bases in the newly synthesized DNA is AATTCCCGG

Which one of the following represents the sequence of bases on the complementary strand? A) GGCCAAATT B) UUTTCCCGG C) AATTCCCGG D) UUAAGGGCC E) TTAAGGGCC

Biology & Microbiology

How does crossing-over during meiosis contribute to genetic variation?

A. Each cell created has chromosomes only from a single parent. B. Crossing-over always causes loss of some genetic information. C. Because genes will be in a new order on some chromosomes,additional DNA will need to be made. D. The exchange of genetic material between homologous chromosomes means that a single chromosome now combines genetic information from both parents.

Biology & Microbiology