Why is Burkitt lymphoma such an aggressive malignancy?

a. Cells readily metastasize to bone marrow.
b. Cells have a high proliferative rate.
c. Cells fail to mature to functional immunophenotype.
d. Cells destroy red cells.


ANS: B
Burkitt lymphoma cells have a high proliferative rate, with a very short doubling time; almost all the malignant cells are in active phases of the cell cycle at any one time.

Health Professions

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