An older client who is prescribed terazosin (Hytrin) for treatment of benign prostatic hyperplasia (BPH) asks the nurse the reason why this drug should initially be taken at bedtime. Which rationale will the nurse base the response to the client?

1. It can cause a sudden fall in blood pressure.
2. It can depress the vasomotor center in the brain.
3. It can decrease the blood supply to the kidneys.
4. It can reduce the formation of urine at bedtime.


Correct Answer: 1
Rationale 1: Terazosin (Hytrin) can cause a sudden fall in blood pressure. First-dose syncope generally occurs 30 to 90 minutes after an initial dose of 2 mg or more, which causes a sudden fall in blood pressure.
Rationale 2: Terazosin (Hytrin) is an alpha-adrenergic blocker that blocks the alpha receptors peripherally. It does not affect the vasomotor center.
Rationale 3: Terazosin (Hytrin) is an alpha-adrenergic blocker that blocks the alpha receptors peripherally. It does not affect the blood vessels to the kidney.
Rationale 4: Terazosin (Hytrin) does not affect the formation of urine in the kidney tubules. It relaxes the smooth muscle of the urinary tract and the bladder, increasing urinary frequency.
Global Rationale: Terazosin (Hytrin) can cause a sudden fall in blood pressure. First-dose syncope generally occurs 30 to 90 minutes after an initial dose of 2 mg or more, which causes a sudden fall in blood pressure. Terazosin (Hytrin) is an alpha-adrenergic blocker that blocks the alpha receptors peripherally. It does not affect the vasomotor center or the blood vessels to the kidney. Terazosin (Hytrin) does not affect the formation of urine in the kidney tubules. It relaxes the smooth muscle of the urinary tract and the bladder, increasing urinary frequency.

Nursing

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