A nurse is teaching a class on X-linked recessive disorders. Which of the following statements would the nurse most likely include?
A) Males are typically carriers of the disorders.
B) No male-to-male transmission occurs.
C) Daughters are more commonly affected with the disorder.
D) Both sons and daughters have a 50% risk of the disorder.
B
Feedback:
Most X-linked disorders demonstrate a recessive pattern of inheritance. Males are more affected than females. A male has only one X chromosome and all the genes on his X chromosome will be expressed, whereas a female will usually need both X chromosomes to carry the disease. There is no male-to-male transmission (since no X chromosome from the male is transmitted to male offspring), but any man who is affected will have carrier daughters. If a woman is a carrier, there is a 50% chance that her sons will be affected and a 50% chance that her daughters will be carriers.
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