At rest, neurons exhibit a negative membrane potential. Among the factors that maintain this polarity, assess which is most DIRECTLY responsible for the difference between intracellular and extracellular ion concentrations?
A. passive leakage of K+ ions across the membrane.
B. movement of K+ ions through voltage-gated K+ channels.
C. passive leakage of Na+ ions across the membrane.
D. movement of Na+ ions through voltage-gated Na+ channels.
E. movements of negatively charged proteins and nucleic acids across the membrane.
Answer: A
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