What physiologic abnormality is believed to be the cause of persistent pulmonary hypertension of the newborn (PPHN)?
a. Right-to-left shunting
b. High cardiac output
c. High pulmonary vascular resistance
d. Metabolic acidosis
ANS: C
The common denominator in PPHN is a return to fetal circulatory pathways, usually because of high PVR.
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