Ordered: Esmolol 5 g in 500 mL D5W to infuse at 125 mg/min for a patient weighing 135 lb. The maximum safe dose of Esmolol is 400 mcg/kg/min. If this is a safe dose, calculate the flow rate: ________. If the ordered dose is not a safe dose, write: not safe.
Fill in the blank(s) with the appropriate word(s).
not safe
Convert weight to kg:
1 kg : 2.2 lb = x : 135 lb, rounded to 61.4 kg
Convert mcg to mg:
1 mg : 1,000 mcg = x : 400 mcg
x = 0.4 mg
Convert g to mg:
1,000 mg : 1 g = x : 5 g
x = 5,000 mg
Calculate mg/kg/min (desired dose):
D = 24.56 mg/min, rounded to 24.6 mg/min is the safe maximum dose
The ordered dose of 125 mg/min is higher than the maximum safe dose of 24.6 mg/min, so this is not a safe dose for this patient.
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