As a member of the stroke team at your institution, you know that the contraindications for thrombolytic therapy include what? (Mark all that apply.)
A) INR above 1.0
B) Recent intracranial pathology
C) Symptom onset greater than 2 hours prior to admission
D) Current anticoagulation therapy
E) Symptom onset greater than 3 hours prior to admission
Ans: B, D, E
Feedback: Some of the absolute contraindications for thrombolytic therapy include symptom onset greater than 3 hours before admission, a patient who is anticoagulated (with an INR above 1.7), or a patient who has recently had any type of intracranial pathology (eg, previous stroke, head injury, trauma). Therefore options A and C are incorrect.
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