The nurse is studying the process whereby antibodies are made in the body. If the body immediately responds to an offending organism, this means the body:
1. Has been exposed before and responds with secondary immunity.
2. Has an overproduction of plasma cells.
3. Is unable to differentiate self from non-self.
4. Has immune tolerance.
Has been exposed before and responds with secondary immunity.
Rationale: B cells must be activated or told to make specific antibodies. If a B cell recognizes an antigen and immediately makes antibodies, this means the body has been exposed to the organism before and responds with secondary immunity. Plasma cells are B cells found in the plasma and make a group of antibodies called immunoglobulins. The inability to differentiate self from non-self is a considered a lack of immune tolerance. Immune tolerance is defined as the ability of the immune system to tolerate all self antigens while retaining the ability to have an effective immune response to non-self antigens.
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