The nurse in charge of a clinical study welcomes the participants in an open forum. One client is surprised that there are men and women from several ethnic groups
The nurse tells the group that in the past, ethnic variables were largely unknown or ignored for which reasons?
1. Clinical trials failed to include ethnically diverse subjects.
2. Clinical trials comprised mostly Caucasian males.
3. Little attention was focused on identifying the different effects drugs had on various ethnic groups.
4. Research proved there were no differences among ethnic groups.
5. The large majority of clinical trials included Caucasian females.
Correct Answer: 1,2,3
Rationale 1: There was a lack of ethnic diversity in early clinical trials.
Rationale 2: Until recently, clinical trials comprised mostly Caucasian males.
Rationale 3: Little attention was focused on identifying the differences in pharmacologic effects in diverse ethnic groups.
Rationale 4: There was insufficient research to show differences because little attention was focused on these differences.
Rationale 5: The large majority of clinical trials excluded females.
Global Rationale: There was a lack of ethnic diversity in early clinical trials. Until recently, clinical trials comprised mostly Caucasian males. Little attention was focused on identifying the differences in pharmacologic effects in diverse ethnic groups. There was insufficient research to show differences because little attention was focused on these differences. The large majority of clinical trials excluded females.
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