Due to her progressing osteoarthritis (OA), an 80-year-old woman is no longer able to perform her activities of daily living without assistance

Which of the following phenomena most likely underlies the woman's situation?
A)
Inappropriate T-cell-mediated immune responses have resulted in articular cartilage degeneration.
B)
Loss of articular cartilage and synovitis has resulted from inflammation caused when joint cartilage attempted to repair itself.
C)
Excessive collagen deposits have accumulated in the woman's synovial joints.
D)
Bone overgrowth in synovial joints has resulted in fusing of adjacent bones that normally articulate.


Ans:
B

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The joint changes associated with osteoarthritis, which include a progressive loss of articular cartilage and synovitis, result from the inflammation caused when cartilage attempts to repair itself, creating osteophytes or spurs. These changes are accompanied by joint pain, stiffness, limitation of motion, and in some cases by joint instability and deformity. Immune etiology is more associated with rheumatoid arthritis, and collagen deposits are characteristic of scleroderma. Bones do not tend to fuse in the pathogenesis of OA.

Nursing

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