A client is undergoing a diagnostic workup to rule out multiple myeloma. Which of the following diagnostic findings would confirm the diagnosis of multiple myeloma?
A) Plasma cells greater than 10% on bone marrow biopsy
B) Decreased production of bone osteoblasts
C) T-cell lymphocyte level of 34% (normal)
D) Immunoglobulin A level of 200 mg/dL (normal)
Ans: A
Feedback:
Multiple myeloma is a plasma cell malignancy that results in proliferation of a single monoclonal immunoglobulin. Multiple myeloma cells are found in the marrow and as osteolytic lesions in all bones. B-cell lymphocytes normally stimulate plasma cells to produce immunoglobulin when needed; T cells are not involved in the process.
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