The physiology instructor asks the students, "How does growth factor affect cell proliferation?" Which students have the most accurate responses? Growth factors: Select all that apply

A) Regulate the inflammatory process
B) Act as a chemoattractant for many cells like neutrophils and macrophages
C) Inhibit the beginning stages of cell changes that can result in cancer
D) Stimulate new blood vessel growth
E) Inhibit cell proliferation


Ans: A, B, D
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The term growth factor is generally applied to small proteins that increase cell size and cell division. In addition to cell proliferation, most growth factors have other effects. They assist in regulating the inflammatory process; serve as chemoattractants for neutrophils, monocytes (macrophages), fibroblasts, keratinocytes, and epithelial cells; stimulate angiogenesis; and contribute to the generation of the ECM.

Health & Biomechanics

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