A client with cardiac disease is prescribed isoproterenol (Isuprel). Which medications, if also prescribed to the client, would cause the nurse to question this order?
Standard Text: Select all that apply.
1. Potassium-wasting diuretic
2. Cardiotonic
3. Anticoagulant
4. Antihyperglycemic
5. Antibiotic
Correct Answer: 1,2
Rationale 1: Isoproterenol (Isuprel) should not be concurrently administered with potassium-wasting diuretics because hypokalemia may result.
Rationale 2: Isoproterenol (Isuprel) may lower serum levels of digoxin and induce dysrhythmias.
Rationale 3: Isoproterenol (Isuprel) does not interact with anticoagulants.
Rationale 4: Isoproterenol (Isuprel) does not interact with antihyperglycemic agents.
Rationale 5: Isoproterenol (Isuprel) does not interact with antibiotics.
Global Rationale: Isoproterenol (Isuprel) should not be concurrently administered with potassium-wasting diuretics because hypokalemia may result. Isoproterenol (Isuprel) may lower serum levels of digoxin and induce dysrhythmias. Isoproterenol (Isuprel) does not interact with anticoagulants, antihyperglycemic agents, or with antibiotics.
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