In a discussion about cancer, a student asks why the body does not phagocytize a tumor. What would be the instructor's best response?
A) "Sometimes tumor cells trick the T cells into allowing them to survive."
B) "Some tumor cells do not develop an antigen–antibody reaction."
C) "Some tumor cells develop a strong mast cell reaction."
D) "Tumor cells are too small to be seen by the immune system."
A
Feedback:
Neoplasms occur when mutant cells escape normal surveillance of the immune system and begin to grow and multiply. Aging reduces efficiency of the immune system; location of mutant cells can make it difficult for lymphocytes to get to them or that mass can grow so quickly that the tumor becomes too large for the immune system to deal with. Tumors can produce antibodies that cover antigen receptor sites on the tumor and prevent recognition by cytotoxic T cells, or a weak antigenic tumor may elicit a mild response from the immune system and tricks the T cells into allowing it to survive.
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