Prior to administering dopamine the nurse reviews a patient's current medication history. For which medications would dopamine cause a drug–drug interaction?
1. MAO inhibitor
2. Phenytoin
3. Beta blocker
4. Digoxin
5. Aspiring
Correct Answer: 1,2,3,4
Rationale 1: Concurrent administration with MAO inhibitors increases the alpha-adrenergic effects of dopamine.
Rationale 2: Phenytoin may decrease the action of dopamine.
Rationale 3: A beta blocker may inhibit the inotropic effect of dopamine.
Rationale 4: Digoxin may increase the risk of dysrhythmias in the patient.
Rationale 5: There is no evidence to suggest a drug–drug interaction will occur if dopamine is administered to a patient who takes aspirin.
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