Explain why the probability of fixation of a new beneficial allele is independent of pop-ulation size in Haldane's model of selection and drift
What will be an ideal response?
ANS:
In small populations, the single new allele has a relative high frequency and is thus more likely to be fixed by drift. However, selection plays a more limited role on small populations so the allele is unlikely to be fixed by selection. In larger populations, the frequency of a new mutation is low, and is therefore unlikely to be fixed by drift. In contrast, selection operates best in large populations and selection will likely lead to fixation of the new allele.
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