You are working to characterize a novel protein in mice. Analysis shows that high levels of the primary transcript that codes for this protein are found in tissue from the brain, muscle, liver, and pancreas. However, an antibody that recognizes the C-terminal portion of the protein indicates that the protein is present in brain, muscle, and liver, but not in the pancreas. What is the most likely explanation for this result?
A. The transcript is immediately degraded in the pancreas.
B. The transcript receives a 3' poly-A tail in the pancreas.
C. The gene that codes for this protein is not transcribed in the pancreas.
D. Alternative splicing in the pancreas creates a protein missing the domain that the antibody recognizes.
E. The transcript receives a 5' cap in the pancreas.
Answer: D
You might also like to view...
Which of the following statements is true?
A) A band of ribosomes determines where a cell plate will form in a dividing plant cell. B) The way in which a plant cell differentiates is determined by the position of the nucleus in the developing plant cell. C) Homeotic genes often control morphogenesis. D) Plant cells differentiate because the cytoskeleton determines which genes will be turned "on" and "off." E) The giant sequoia was the first plant to have its genome sequenced.
Now, time rolls inexorably along. One hundred thousand years after the original event, yet more rodent-philic descents return to the island and repeat the sampling process
There are now twice as many fixed differences between A1 and A2, relative to the 50,000 years after vicariant event table. Unlike last time, you find that individuals from A1 cannot reproduce with individuals from A2. Compare the DNA sequences presented above and give the amount of variation expected: ...between two randomly chosen individuals of A1. A. relatively low variation B. moderate variation C. relatively high variation
Where does the citric acid cycle take place in a eukaryotic cell?
a. nucleus b. cytosol c. mitochondrial matrix d. endoplasmic reticulum e. mitochondrial membrane
Which statement is NOT true about the human respiratory system?
A. The glottis is closed by the forward movement of the soft palate during swallowing. B. Food and air both enter the pharynx, presenting a potential danger to respiration. C. The glottis is the passageway through the larynx by which air enters the trachea. D. Air reaching the lungs has been warmed to body temperature by passage through the nose and upper respiratory passageways. E. Cilia and hairs in the nose help to filter out foreign materials in the air.