Explain how dicer and RISC are involved in the production and function of miRNAs

What will be an ideal response?


Once the pre-miRNA is transcribed, dicer removes the loop to produce a short double-stranded RNA
molecule. A protein complex that includes the RISC protein degrades one of the two RNA strands,
leaving a single-stranded miRNA. This protein-miRNA complex binds to other mRNAs. If the pairing
is imperfect, translation of that mRNA is blocked. If the pairing is perfect, the mRNA is destroyed.

Biology & Microbiology

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A statement, "in prokaryotes, translation is coupled to transcription" simply means

a. RNA translation occurs before DNA transcription b. RNA polymerase is tightly bind to DNA c. translation and transcription occurs in the cytoplasm d. DNA transcription and RNA translation occurs simultaneously

Biology & Microbiology

Precancerous growths in the colon are known as ________; these can usually be removed surgically

Fill in the blank(s) with correct word

Biology & Microbiology

A(n) ________ is a category of the classification system of organisms that can include multiple kingdoms

Fill in the blank(s) with correct word

Biology & Microbiology

In metaphase I ________ are aligned along the metaphase plate, and in metaphase II ________ are aligned along the metaphase plate

A) homologous chromosomes; tetrads B) homologous chromosomes; pairs of sister chromatids C) maternal chromosomes; paternal chromosomes D) pairs of sister chromatids; homologous chromosomes

Biology & Microbiology