Which of the following is true regarding reference ranges?
a. Should be derived from reference books
b. Need to be determined only for adults
c. Can be established by running the test procedure on 10 healthy people
d. Are ranges of values for an analyte in normal healthy people
ANS: D
Reference ranges should be determined by evaluating a group of perhaps as many as 120 normal healthy people for the same analyte. If the analyte differs in different groups, based on data such as age and sex, then it must be determined for each group if at all possible.
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