A 12-year-old female of Hispanic descent enters the emergency department with severe pain on the left side of her abdomen. The family has recently immigrated to the United States
First attempts at pain relief with nonnarcotic drugs were unsuccessful. Opioids are needed to suppress the pain. Her laboratory results show that she is anemic and her parents reveal a history of chronic infections and a stroke. Genetic testing reveals that her hemoglobin gene has a single amino acid substitution of valine for glutamic acid. Her primary diagnosis is:
A. blunt traumatic injury to the spleen
B. aneurysm
C. sickle cell disease
D. cystic fibrosis
ANS: C
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