Would ID50 and LD50 necessarily be the same for a given virus? Why or why not?

A. Yes, because the number of viruses that infect 50% of a test population should also kill 50% of that test population.
B. No, because a virus may be highly infectious (very low ID50 value) but only marginally lethal (very high LD50 value). A prime example of this is the rhinovirus (common cold virus).
C.
No, because very few viruses are lethal, yet many are highly infectious. The two values should ALWAYS be different.

D. Yes, because what we're actually describing here is infection/killing of individual CELLS, not of entire organisms. If a cell is infected, it will always be killed.


B

Biology & Microbiology

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