A heterozygote could have a variety of phenotypes depending on whether or not the mutation is recessive, dominant, or haploinsufficient. In this example, the gene A is necessary to form a tail in mice. If the mouse is a heterozygote (A/a), then what

would you predict the phenotype to be if the mutation was recessive, dominant, or haploinsufficient.

What will be an ideal response?


If the mutation is recessive, then the phenotype should be similar to wild type, and tail development should be unaffected. If the mutation is dominant, then the A/a mouse would likely have no tail. If the mutation is haploinsufficient, then one might predict an abnormal tail (perhaps shorter or misshaped).

Biology & Microbiology

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