What are the three key elements for determining F, a measure that a particular allele is IBD, using pedigree analysis?

What will be an ideal response?


The three key elements to determining F from pedigrees are (1 ) the number of alleles of a gene carried by common ancestors, (2 ) the number of transmission events required to produce a genotype that is homozygous IBD, and (3 ) the probability of transmission for each event linking the allele in a common ancestor to the inbred individual. First-cousin mating is a form of inbreeding that is relatively common in many human societies and is common in mammals in general.

Biology & Microbiology

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Biology & Microbiology

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Biology & Microbiology

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Biology & Microbiology