A man who has a Y-linked disorder has married a healthy woman. The couple is concerned about passing the man's disorder to their children. What should the nurse consider before responding to this concern?
1. Only the female children will be affected.
2. Female fetuses with this genotype do not survive to birth.
3. Only male children will be affected.
4. The chance the father will pass the disease on to male children is 1 in 2.
3
Rationale 1: Females cannot be affected because the disorder requires a Y chromosome.
Rationale 2: The female fetus cannot have this genotype as it requires a Y chromosome.
Rationale 3: Because the disorder is Y-linked, only males are affected.
Rationale 4: The father has only one Y chromosome to contribute, so the affected chromosome will be passed to each son.
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