The initial rate of distribution of a drug is heavily dependent on the ________________ to various organs

A. blood flow
B. hepatic portal circulation
C. oxygen distribution
D. reactions


a
Rationale: The blood flow is the most important factor here in distributing a drug to various organs.
Hepatic portal circulation concerns primarily the liver. Distribution is not a focused answer. "Reactions" is incorrect because it is not an accurate word to be used in this scenario.

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