Considering its MOA, what might be the most likely mechanism that would explain the development of resistance to gefitinib in a tumor?
A. Overexpression of DNA repair enzymes
B. Overexpression of glutathione S-transferase
C. Mutation of the epidermal growth factor receptor
D. Overexpression of multidrug resistance protein
E. Downregulation of CYP3A4 in the tumor
Ans: C. Mutation of the epidermal growth factor receptor
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A nurse is explaining the purpose of a bone marrow biopsy (BMB) to a client. The information the nurse provides is that a bone marrow biopsy is done to evaluate
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Matthew is 7 years old. He is scheduled to have surgery next week. The nurses on the unit offer to give Matthew and his parents a tour of the unit. This is:
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