Which of the following statements is a REASONABLE mechanism?

A. Downregulation of P-glycoprotein pump leads to taxol resistant tumors
B. Gleevec is potent inhibitor of p53.
C. lrinotecan inhibits topoisomerase I
D. Methotrexate is a G2-specific cancer chemotherapeutic
E. Vinblastine causes increased stability of microtubules


Ans: C. lrinotecan inhibits topoisomerase I

Nursing

You might also like to view...

When performing newborn resuscitation, which action would the nurse do first?

A) Intubate with an appropriate-sized endotracheal tube. B) Give chest compressions at a rate of 80 times per minute. C) Administer epinephrine intravenously. D) Suction the mouth and then the nose.

Nursing

A woman who delivered her third child yesterday has just learned that her two school-age children have contracted chickenpox. What should the nurse tell her?

a. The woman's two children should be treated with acyclovir before she goes home from the hospital. b. The baby will acquire immunity from the woman and will not be susceptible to chickenpox. c. The children can visit their mother and sibling in the hospital as planned but must wear gowns and masks. d. The woman must make arrangements to stay somewhere other than her home until the children are no longer contagious.

Nursing

A nurse writes a letter to her congressman about an issue involving health care. In order to be effective with writing a letter to an elected official, a nurse should include what in the first paragraph?

A) Greet the official according to his or her title in the salutation. B) Add personal experiences and views eliminating the tone of a form letter. C) Identify yourself as a constituent, health care expert, and credible source on the issue. D) Provide contact information as legislators monitor letters from their constituents.

Nursing

A 35-year-old client comes to the clinic with complaints of blurred vision and muscle spasms that come and go over the past several months. A critical piece of the client history for the nurse to note is that:

1. The client is from Canada. 2. The client has a family history of epilepsy. 3. The client has been depressed. 4. The client's father had Parkinson's disease.

Nursing