An Alzheimer's patient taking donepezil (Aricept) has a complete blood count that indicates he or she is anemic. What drug taken in combination with donepezil could be the cause of the anemia?
A) Cimetidine (Tagamet)
B) Ibuprofen (Advil)
C) Diltiazem (Cardizem)
D) Furosemide (Lasix)
B
Feedback:
There could be an increased risk of gastrointestinal (GI) bleeding if donepezil is taken with a nonsteroidal anti-inflammatory drug (NSAID) because of the combination of increased GI secretions and the GI mucosal erosion associated with the use of NSAIDs. Cimetidine, diltiazem, and furosemide would not affect GI bleeding.
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