The home care nurse is taking care of a patient on IV vancomycin for cellulitis of the left calf. How would the nurse explain how microorganisms develop resistance to anti-infective medications?
A) Microorganisms can alter the blood supply to the infection.
B) Microorganisms can stop the cell from reproducing.
C) Microorganisms produce a chemical that acts as an antagonist to the drug.
D) Microorganisms change their cell membrane to make it look like the drug.
C
Feedback:
Microorganisms develop resistance in a number of ways, including the following: changing cellular permeability to prevent the drug from entering the cell or altering transport systems to exclude the drug from active transport into the cell; altering binding sites on the membranes or ribosomes, which then no longer accept the drug; and producing a chemical that acts as an antagonist to the drug. Microorganisms do not alter the blood supply to the infection, stop a cell from reproducing, or change the appearance of the cell membrane.
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