Which of the following statements about thalassemia is true?
a. It involves the inheritance of dominant genes from both parents.
b. It is characterized by an impaired rate of hemoglobin chain synthesis.
c. It always involves early death.
d. It involve years of transfusions, which cause few side effects if any.
B
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A Incorrect. Thalassemia does not involve dominant genes.
B Correct. The thalassemias are a group of inherited autosomal recessive disorders, characterized by an impaired rate of hemoglobin chain synthesis.
C Incorrect. If children with this disorder are not treated, they will die by the age of 5 to 6 years; but, their life can be extended with treatments by 1 to 2 decades.
D Incorrect. Treatment of thalassemia involves years of transfusions with often severe side effects.
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