Which adverse effects does the nurse anticipate for a client who is receiving long-term therapy with corticosteroids? (Select all that apply.)
Note: Credit will be given only if all correct choices and no incorrect choices are selected.
1. Delayed wound healing
2. Diarrhea
3. Increased risk for infections
4. Sodium retention
5. Nausea
Correct Answer: 1, 3, 4
Rationale 1: Significant adverse effects can occur during long-term therapy with corticosteroids. An array of signs and symptoms known as Cushing's syndrome includes adrenal atrophy, osteoporosis, increased risk of infections, delayed wound healing, peptic ulcers, and a redistribution of fat around the shoulders and neck. Mood and personality changes can occur, with the client becoming psychologically dependent upon the therapeutic effects of the drug. Some of the glucocorticoids, such as hydrocortisone, also have mineralocorticoid activity, and can cause retention of sodium and water.
Rationale 2: Diarrhea is not an adverse effect related to corticosteroids.
Rationale 3: Significant adverse effects can occur during long-term therapy with corticosteroids. An array of signs and symptoms known as Cushing's syndrome includes adrenal atrophy, osteoporosis, increased risk of infections, delayed wound healing, peptic ulcers, and a redistribution of fat around the shoulders and neck. Mood and personality changes can occur, with the client becoming psychologically dependent upon the therapeutic effects of the drug. Some of the glucocorticoids, such as hydrocortisone, also have mineralocorticoid activity, and can cause retention of sodium and water.
Rationale 4: Significant adverse effects can occur during long-term therapy with corticosteroids. An array of signs and symptoms known as Cushing's syndrome includes adrenal atrophy, osteoporosis, increased risk of infections, delayed wound healing, peptic ulcers, and a redistribution of fat around the shoulders and neck. Mood and personality changes can occur, with the client becoming psychologically dependent upon the therapeutic effects of the drug. Some of the glucocorticoids, such as hydrocortisone, also have mineralocorticoid activity, and can cause retention of sodium and water.
Rationale 5: Nausea is not an adverse effect of corticosteroids.
Global Rationale: Significant adverse effects can occur during long-term therapy with corticosteroids. An array of signs and symptoms known as Cushing's syndrome includes adrenal atrophy, osteoporosis, increased risk of infections, delayed wound healing, peptic ulcers, and a redistribution of fat around the shoulders and neck. Mood and personality changes can occur, with the client becoming psychologically dependent upon the therapeutic effects of the drug. Some of the glucocorticoids, such as hydrocortisone, also have mineralocorticoid activity, and can cause retention of sodium and water. Diarrhea and nausea are not adverse effects of corticosteroids.
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