A nurse is teaching a group of nursing students about neuropharmacology. Which statement by a student about peripheral nervous system (PNS) drugs indicates a need for further teaching?
a. "Drugs affecting axonal conduction have a variety of uses."
b. "Drugs that alter synaptic transmission can be highly selective."
c. "Many PNS drugs act by altering synaptic transmission."
d. "These drugs work by influencing receptor activity."
ANS: A
Local anesthetics are the only drugs shown to work by altering axonal conduction. Any drug affecting axonal conduction would be nonselective, because axonal conduction of impulses is essentially the same in all neurons. In contrast, drugs that affect synaptic transmission can be highly selective, because each transmitter has different effects on receptor sites. Most PNS drugs work on synaptic transmission processes. Through their effects on transmitters, they influence receptor activity.
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