What observation first suggested that H2A and H2B formed heterodimers?

What will be an ideal response?


A milder protein purification technique that did not denature the histones resulted in two peaks upon purification, one containing H2A and H2B and one containing H3 and H4 . This observation suggested that they were physically associated in some way and lead Kornberg to carry out his crosslinking experiments.

Biology & Microbiology

You might also like to view...

Testing subsets of a population allows scientists to

make_______ about the whole population. a. theories b. hypotheses c. generalizations d. conclusions e. all of these

Biology & Microbiology

Which of the following misconceptions about evolution can be refuted with the molecular evidence that is being collected through DNA analysis?

A. Evolution is not observable or testable, thus it is not science. B. Evolution proposes life changed as a result of random events; traits are too complex to have originated by chance alone. C. Evolution is a theory about how life originated. D. There are no transitional fossils.

Biology & Microbiology

A microarray of thousands of DNA sequences stamped onto a glass plate is a ____

a. Polysome b. DNA chip c. Plasmid d. Polygene e. DNA plate

Biology & Microbiology

The earliest vascular plants on land had underground stems (rhizomes) but no roots. Water and mineral nutrients were most likely obtained by _____

A) diffusion through stomata B) absorption by mycorrhizae C) osmosis through the root hairs D) diffusion across the cuticle of the rhizome

Biology & Microbiology