Explain the purpose of tamoxifen in breast cancer treatment

What will be an ideal response


Tamoxifen binds to estrogen receptors and inhibits estrogen-mediated tumor growth. Breast cancer cells that are well-differentiated and ER+ (estrogen receptor positive) will regress under tamoxifen, whereas the drug is ineffective against poorly-differentiated ER- tumors. Biopsy specimens are routinely tested for ER status to inform therapy. Recent studies have also shown benefit to patients taking tamoxifen for "pre-invasive" conditions such as DCIS (ductal carcinoma in situ) which are often the best-differentiated and more ER sensitive tumor cells of all.

Anatomy & Physiology

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Tapeworms are round

Indicate whether the statement is true or false

Anatomy & Physiology

The period of sexual and physical maturation is (the)

A) infancy. B) childhood. C) senescence. D) adolescence. E) neonatal period

Anatomy & Physiology

The indicators that are essential for human life include all of the following EXCEPT ________.

A. coloring B. heart rate C. respirations D. temperature

Anatomy & Physiology

Structures that connect lymphatic capillary cells to surrounding tissue and prevent the capillaries from collapsing are called _________ filaments

Fill in the blank with correct word.

Anatomy & Physiology