A patient asks the health care provider how a histamine2-receptor antagonist (H2RA) works. Which of the following responses should the health care provider offer?
a. The drug neutralizes gastric acid.
b. The drug coats the irritated gastric mucosa lining.
c. The drug inhibits gastric acid secretion.
d. The drug tightens the lower esophageal sphincter.
ANS: C
H2RAs inhibit the action of histamine at histamine2 (H2) receptors, thereby inhibiting gastric acid secretion and reducing total pepsin output. The resulting decrease in acid permits healing of ul-cerated areas.
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