The main mechanism of action of alkylating agents is
1. they stimulate the body's immune system.
2. unknown.
3. they change the shape of the DNA double helix and prevent nucleic acid from completing normal cell division.
4. they disrupt metabolic pathways.
Correct Answer: 3
Rationale 1: This is representative of pharmacotherapy with biologic response modifiers, immune therapies, and miscellaneous antineoplastics.
Rationale 2: The mechanism of hormonal antineoplastic activity is largely unknown.
Rationale 3: Alkylation changes the shape of the DNA double helix and prevents the nucleic acid from completing normal cell division.
Rationale 4: This is representative of the antimetabolites.
You might also like to view...
A patient is prescribed an immunosuppressive agent. Which statement indicates the patient needs additional instruction from the nurse about this drug?
1. "I should drink a lot of fruit juices, such as grapefruit juice." 2. "I know to call the physician if I start experiencing a lot of bruising." 3. "I should drink plenty of water to keep from getting dehydrated." 4. "If I experience any joint pain, I should take ibuprofen for the pain as needed every 4 hours."
You are the nurse interviewing a potential blood donor. You ask the client what medications he uses (prescription, over the counter, blood thinners, recent immunization, and illicit). What is the purpose of this question?
1. Medications can pass from blood donor to recipient in the donated blood. 2. To educate the blood donor about risks associated with illicit drug use. 3. The physician at the blood bank must be notified of all drug use in potential donors. 4. A list of medications will be placed on the bag of donated blood.
Which of the following is likely to cause orthostatic hypotension in older adults?
A) Decreased baroreceptor response B) Decreased compliance/stiffer vessels C) Increased peripheral vascular resistance D) Rigid arteries
Round your answer to the nearest tenth. Nesiritide is infusing at 18 mL/h for a patient with congestive heart failure. The nesiritide bag has a 1.5 mg/250 mL concentration
How many micrograms per kilogram per minute is the nesiritide infusing for a 70-kg patient? _______________ Fill in the blank(s) with correct word