Compare and contrast ionotropic and metabotropic receptors.
What will be an ideal response?
Ans: Physical proximity to parts of neuron where effects exerted (ionotropic: Attached to ion channel; metabotropic: Separated from ion channels and other proteins)
Type of effect (ionotropic: Open ion channel; Uses G protein to activate ion channels and effector enzymes)
Duration of effect (ionotropic: Ends when neurotransmitter leaves binding site; metabotropic: Effector enzymes engage a cascade of events that persist after neurotransmitter leaves receptor)
Impact on a neuron (ionotropic: Influx of ions changes local potential; metabotropic:Can affect local potentials; also has other effects, including enzyme regulation, gene expression, and protein synthesis)
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Fill in the blank(s) with correct word
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