A patient with Cushing's syndrome undergoes irradiation of the pituitary gland. During the months required for the irradiation to produce its effect on the pituitary gland, the patient may be treated adjunctively with
a. dexamethasone.
b. fludrocortisone acetate (Florinef).
c. ketoconazole (Nizoral).
d. cosyntropin.
C
Ketoconazole is the most effective inhibitor of glucocorticoid synthesis available.
Dexamethasone is used for replacement therapy, for treating nonendocrine disorders, and for the diagnosis of adrenal dysfunction.
Fludrocortisone acetate, a potent mineralocorticoid, is the drug of choice for chronic mineralo-corticoid replacement. It is used to treat Addison's disease and primary hypoaldosteronism.
Cosyntropin mimics the effects of human ACTH. It is not indicated for Cushing's disease, but rather is used primarily for diagnostic tests.
You might also like to view...
A new mother asks why she has to open a new bottle of formula for each feeding. The nurse's best response is:
a. "This makes it easier to keep track of how much the baby is taking." b. "Formula loses some nutritional value once it is opened." c. "Bacteria can grow rapidly in warm milk." d. "Formula may turn sour after it is opened."
The nurse is preparing discharge instructions for a client with an open surgical wound. Which instructions are important for the nurse to include for this client?
Select all that apply. A) Apply lubricating lotion to the edges of the wound. B) Notify your doctor if you notice edema, heat, or tenderness at the wound site. C) Thoroughly irrigate the wound with hydrogen peroxide. D) Wash hands before and after changing the surgical dressing. E) Adjust your diet to increase the amount of protein.
The nurse is admitting a 25-year-old client to the emergency department with partial-thickness injuries over 20% of the total body surface area, involving both lower legs. This injury is classified as:
1. A moderate burn. 2. A minor burn. 3. A major. 4. A severe burn.
The management of cryptorchidism usually involves which of the following interventions?
a. observation while awaiting spontaneous descent of the testes in the first year after birth b. large doses of testosterone given daily c. orchiopexy surgery performed as soon as possible after detection of the cryptorchidism d. downward massaging of the testis involved to encourage downward migration