A patient presents to the walk-in clinic complaining of vomiting and burning in her mid-epigastria. The nurse knows that in the process of confirming peptic ulcer disease, the physician is likely to order a diagnostic test to detect the presence of what?
A) Infection with Helicobacter pylori
B) Excessive stomach acid secretion
C) An incompetent pyloric sphincter
D) A metabolic acid–base imbalance
Ans: A
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H. pylori infection may be determined by endoscopy and histologic examination of a tissue specimen obtained by biopsy, or a rapid urease test of the biopsy specimen. Excessive stomach acid secretion leads to gastritis; however, peptic ulcers are caused by colonization of the stomach by H. pylori. Sphincter dysfunction and acid–base imbalances do not cause peptic ulcer disease.
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