Which drug is used to obtain vasodilation in the treatment of chronic heart failure?
a. ACTH
b. ACE inhibitors
c. ARBs
d. ANB agents
ANS: B
Angiotensin converting enzyme (ACE) inhibitors are the mainstays of oral vasodilator therapy for treating chronic heart failure. ACTH is adrenocorticotropic hormone, secreted by the anterior pituitary to stimulate the adrenal cortex. ARBs are angiotensin reuptake blockers, used for the treatment of hypertension. ANB agents are adrenergic neuron blocking agents, such as guanethidine, given for the treatment of hypertension.
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