After teaching a group of nursing students about the half-life of a drug, the instructor determines the need for additional teaching when the students identify which of the following as true? Select all that apply:
A) Half-life can be decreased in clients with renal disease.
B) Half-life can help determine dosing frequency.
C) Half-life does not change throughout a client's life.
D) Liver disease can increase half-life.
E) Half-life is the measure of the rate at which drugs are removed from the body.
Ans: A, C
Feedback:
Half-life is the measure of the rate at which drugs are removed from the body, and any difficulty in excreting a drug increases half-life, including liver or kidney disease or advanced age.
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